National Alcohol Indicators bulletin 16 documents numbers and trends for alcohol-attributable deaths and hospitalisations across all Australian jurisdictions using the latest Burden of Disease Methods. The bulletin shows that an estimated 5,785 Australians aged 15+ years died of alcohol-attributable disease and injury in 2015, while hospitalisations attributable to alcohol exceeded 144,000 in 2012/13. Trends in alcohol-attributable deaths appeared to have remained stable or slightly decreased over time. National hospitalisation rates increased marginally between 2003/04 and 2012/13.