This thesis employs post-structuralist and science and technology (STS) theory to critically examine the constitution of methamphetamine and methamphetamine users in scientific, policy, treatment and media texts. Methamphetamine-related practice is also analysed, including how people consume this drug and service provision related to methamphetamine use. The ways in which authoritative discourses shape these practices — how people draw upon, embrace and subvert hegemonic understandings of this drug in their day-to-day lives — are then discussed